A Time Bomb for Leukemia.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 27058656.
- Also identified by DOI 10.1016/j.cell.2016.03.024.
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Abstract
Alterations of the circadian clock have been linked to cancer development. Puram et al. (in this issue) now uncover differential requirements between healthy hematopoietic and diseased leukemic stem cells for core circadian transcription factors, wherein leukemic cells depend on the clock machinery for survival and growth.
Medical subject headings
- Circadian Rhythm
- Transcription Factors