VEGF-B Improves Metabolic Health through Vascular Pruning of Fat.
Level V
Where this comes from
- Record sourced from PubMed, PMID 27076071.
- Also identified by DOI 10.1016/j.cmet.2016.03.012.
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Abstract
Unraveling the mechanism VEGF-receptors modulating metabolism has therapeutic implications. In this issue, Robciuc et al. (2016) demonstrate that VEGF-B, by displacing VEGF-A from VEGFR1 and activating VEGFR2, increases adipose tissue vascularity, improves insulin sensitivity, diminishes obesity, and alleviates metabolic syndrome.
Medical subject headings
- Vascular Endothelial Growth Factor B
- Vascular Endothelial Growth Factor Receptor-2