The Plot Thickens: Diet Microbe Interactions May Modulate Thrombosis Risk.

Martínez-Del Campo, Ana; Romano, Kymberleigh A; Rey, Federico E; Balskus, Emily P · Cell Metab · 2016

editorial · Level V

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Abstract

Thrombosis plays an important role in cardiovascular disease (CVD). Platelet activation is an essential step in the genesis and propagation of atherothrombotic complications. In a recent publication, Zhu and colleagues report that gut microbe-derived TMAO enhances platelet responsiveness and thrombosis, providing a novel mechanistic connection between microbes and CVD (Zhu et al., 2016).

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