Epithelial-Mesenchymal Transition and Immune Evasion during Lung Cancer Progression: The Chicken or the Egg?
editorial · Level V
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- Record sourced from PubMed, PMID 27076625.
- Also identified by DOI 10.1158/1078-0432.CCR-16-0336 and PMC identifier 4947415.
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Abstract
Epithelial-mesenchymal transition (EMT) is a complex process involved in metastasis. Immune evasion is required for tumor progression and is characterized by an ineffective antitumor immune response and upregulation of immune-suppressive signals. The coexistence of EMT and adaptive immune evasion opens the possibility of a mechanistic link between these processes. Clin Cancer Res; 22(14); 3422-4. ©2016 AACRSee related article by Lou et al., p. 3630.
Medical subject headings
- Epithelial-Mesenchymal Transition
- Immune Evasion
- Lung Neoplasms