A research roadmap for next-generation sequencing informatics.

Altman, Russ B; Prabhu, Snehit; Sidow, Arend; Zook, Justin M; Goldfeder, Rachel; Litwack, David; Ashley, Euan; Asimenos, George et al. · Sci Transl Med · 2016

review · Level V

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Abstract

Next-generation sequencing technologies are fueling a wave of new diagnostic tests. Progress on a key set of nine research challenge areas will help generate the knowledge required to advance effectively these diagnostics to the clinic.

Medical subject headings