Engineering Models to Scale.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 27104972.
- Also identified by DOI 10.1016/j.cell.2016.04.017.
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Abstract
Developing organisms can regulate and scale patterns to achieve consistent proportions despite immense changes in size. In this issue, Cao et al. build a model system, using engineered E. coli, to understand how regulatory dynamics can produce pattern scaling without the need for a morphogen gradient.
Medical subject headings
- Body Patterning
- Gene Expression Regulation, Developmental