Photoactive g-C3 N4 Nanosheets for Light-Induced Suppression of Alzheimer's β-Amyloid Aggregation and Toxicity.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 27111552.
- Also identified by DOI 10.1002/adhm.201500964.
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Abstract
Graphitic carbon nitride (g-C3 N4 ) has a suppressive capability toward Alzheimer's Aβ aggregation under light-illumination. Photoinduced electrons of g-C3 N4 generate reactive oxygen resulting in photooxidation of amyloid peptides that blocks Aβ aggregation. Fe doping of g-C3 N4 frameworks results in enhanced optical properties and even stronger inhibition of Aβ aggregation.
Medical subject headings
- Amyloid beta-Peptides
- Nitriles
- Peptide Fragments
- Photochemical Processes
- Protein Aggregation, Pathological
- Reactive Oxygen Species