Dynamic Chiral Nanoparticle Assemblies and Specific Chiroplasmonic Analysis of Cancer Cells.

Zhao, Yuan; Yang, Yaxin; Zhao, Jing; Weng, Ping; Pang, Qingfeng; Song, Qijun · Adv Mater · 2016

basic_science · Level V

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Abstract

Fabricated Ag@Au core-shell nanoparticle (CS NP) assemblies exhibit pronounced and reverse chiral bisignate plasmonic signals spanning 400 to 580 nm, in comparison to Ag NP assemblies. The time-dependent chiro-optical response of assemblies that shift with shell deposition is systematically recorded. Chiral Ag@Au CS NP assemblies first achieve the special discrimination of circulating tumor cells with HER2 overexpression.

Medical subject headings