Tunable Thermal-Sensitive Polymer-Graphene Oxide Composite for Efficient Capture and Release of Viable Circulating Tumor Cells.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 27115557.
- Also identified by DOI 10.1002/adma.201600658 and PMC identifier 5680542.
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Abstract
A highly sensitive microfluidic system to capture circulating tumor cells from whole blood of cancer patients is presented. The device incorporates graphene oxide into a thermoresponsive polymer film to serve as the first step of an antibody functionalization chemistry. By decreasing the temperature, captured cells may be released for subsequent analysis.
Medical subject headings
- Cell Separation
- Graphite
- Neoplasms
- Neoplastic Cells, Circulating
- Oxides
- Polymers
- Temperature