Looping around Reprogramming: The Topological Memory of Induced Pluripotency.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 27152435.
- Also identified by DOI 10.1016/j.stem.2016.04.006.
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Abstract
Genome architecture is associated with cellular identity, but how this organization changes during reprogramming is not well understood. Now in Cell Stem Cell, Krijger et al. (2016) and Beagan et al. (2016) report 3D chromatin interaction maps before and after reprogramming, providing evidence for topological memory in induced pluripotent stem cells.
Medical subject headings
- Cellular Reprogramming
- Induced Pluripotent Stem Cells