MOCAT2: a metagenomic assembly, annotation and profiling framework.

Kultima, Jens Roat; Coelho, Luis Pedro; Forslund, Kristoffer; Huerta-Cepas, Jaime; Li, Simone S; Driessen, Marja; Voigt, Anita Yvonne; Zeller, Georg et al. · Bioinformatics · 2016

basic_science · Level V

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Abstract

MOCAT2 is a software pipeline for metagenomic sequence assembly and gene prediction with novel features for taxonomic and functional abundance profiling. The automated generation and efficient annotation of non-redundant reference catalogs by propagating pre-computed assignments from 18 databases covering various functional categories allows for fast and comprehensive functional characterization of metagenomes. MOCAT2 is implemented in Perl 5 and Python 2.7, designed for 64-bit UNIX systems and offers support for high-performance computer usage via LSF, PBS or SGE queuing systems; source code is freely available under the GPL3 license at http://mocat.embl.de : bork@embl.de Supplementary data are available at Bioinformatics online.

Medical subject headings