TreeQTL: hierarchical error control for eQTL findings.
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- Record sourced from PubMed, PMID 27153635.
- Also identified by DOI 10.1093/bioinformatics/btw198 and PMC identifier 4978936.
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Abstract
: Commonly used multiplicity adjustments fail to control the error rate for reported findings in many expression quantitative trait loci (eQTL) studies. TreeQTL implements a hierarchical multiple testing procedure which allows control of appropriate error rates defined relative to a grouping of the eQTL hypotheses. The R package TreeQTL is available for download at http://bioinformatics.org/treeqtl sabatti@stanford.edu Supplementary data are available at Bioinformatics online.
Medical subject headings
- Quantitative Trait Loci
- Software