gkmSVM: an R package for gapped-kmer SVM.

Ghandi, Mahmoud; Mohammad-Noori, Morteza; Ghareghani, Narges; Lee, Dongwon; Garraway, Levi; Beer, Michael A · Bioinformatics · 2016

basic_science · Level V

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Abstract

We present a new R package for training gapped-kmer SVM classifiers for DNA and protein sequences. We describe an improved algorithm for kernel matrix calculation that speeds run time by about 2 to 5-fold over our original gkmSVM algorithm. This package supports several sequence kernels, including: gkmSVM, kmer-SVM, mismatch kernel and wildcard kernel. gkmSVM package is freely available through the Comprehensive R Archive Network (CRAN), for Linux, Mac OS and Windows platforms. The C ++ implementation is available at www.beerlab.org/gkmsvm mghandi@gmail.com or mbeer@jhu.edu Supplementary data are available at Bioinformatics online.

Medical subject headings