e23D: database and visualization of A-to-I RNA editing sites mapped to 3D protein structures.
basic_science · Level V
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- Record sourced from PubMed, PMID 27153640.
- Also identified by DOI 10.1093/bioinformatics/btw204.
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Abstract
e23D, a database of A-to-I RNA editing sites from human, mouse and fly mapped to evolutionary related protein 3D structures, is presented. Genomic coordinates of A-to-I RNA editing sites are converted to protein coordinates and mapped onto 3D structures from PDB or theoretical models from ModBase. e23D allows visualization of the protein structure, modeling of recoding events and orientation of the editing with respect to nearby genomic functional sites from databases of disease causing mutations and genomic polymorphism. http://www.sheba-cancer.org.il/e23D CONTACT: oz.solomon@live.biu.ac.il or Eran.Eyal@sheba.health.gov.il.
Medical subject headings
- Databases, Protein
- Protein Structure, Tertiary
- Proteins
- RNA Editing