Coala: an R framework for coalescent simulation.
basic_science · Level V
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- Record sourced from PubMed, PMID 27153679.
- Also identified by DOI 10.1093/bioinformatics/btw098.
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Abstract
Simulation programs based on the coalescent efficiently generate genetic data according to a given model of evolution. We present coala, an R package for calling coalescent simulators with a unified syntax. It can execute simulations with several programs, calculate additional summary statistics and combine multiple simulations to create biologically more realistic data. The package is publicly available on CRAN and on https://github.com/statgenlmu/coala under the conditions of the MIT license. metzler@bio.lmu.de.
Medical subject headings
- Computational Biology
- Evolution, Molecular
- Models, Genetic
- Software