Commentary on Verweij et al. (2016): Conduct problems and substance use-genetic and environmental perspectives on sex differences.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 27157903.
- Also identified by DOI 10.1111/add.13371 and PMC identifier 4941623.
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Abstract
Genes influence the covariance between conduct disorder (CD) problems and substance use in males, but shared environment is more important in females. We now need to consider: (a) how genetic influences on CD affect correlations across substances from early to later stages of involvement; (b) whether polygenic liability to CD and substance use overlap; (c) environmental pathways of vulnerability (e.g. peers) in females; and (d) sex effects derived from opposite-sex twin pairs.
Medical subject headings
- Sex Characteristics
- Substance-Related Disorders