ERRγ-A New Player in β Cell Maturation.
Level V
Where this comes from
- Record sourced from PubMed, PMID 27166940.
- Also identified by DOI 10.1016/j.cmet.2016.04.026.
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Abstract
Glucose and hormone responsiveness of pancreatic β cells is acquired during postnatal maturation and is critical for appropriate insulin secretion. In a recent issue of Cell Metabolism, Yoshihara et al. (2016) report that estrogen-related receptor γ (ERRγ) promotes functional maturation of both mouse neonatal β cells and human iPSC-derived β-like cells.
Medical subject headings
- Cell Differentiation
- Insulin-Secreting Cells
- Receptors, Estrogen