Deep Photoacoustic/Luminescence/Magnetic Resonance Multimodal Imaging in Living Subjects Using High-Efficiency Upconversion Nanocomposites.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 27185066.
- Also identified by DOI 10.1002/adma.201506460.
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Abstract
A gadolinium-doped multi-shell upconversion nanoparticle under 800 nm excitation is synthesized with a 10-fold fluorescence-intensity enhancement over that under 980 nm. The nanoformulations exhibit excellent photoacoustic/luminescence/magnetic resonance tri-modal imaging capabilities, enabling visualization of tumor morphology and microvessel distribution at a new imaging depth.
Medical subject headings
- Fluorescence
- Gadolinium
- Luminescent Measurements
- Magnetic Resonance Imaging
- Metal Nanoparticles
- Multimodal Imaging
- Photoacoustic Techniques