Implementation of Molecular Surveillance After a Cluster of Fatal Toxoplasmosis at 2 Neighboring Transplant Centers.
case_series · Level IV
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- Record sourced from PubMed, PMID 27199460.
- Also identified by DOI 10.1093/cid/ciw330 and PMC identifier 4967604.
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Abstract
After a cluster of fatal toxoplasmosis among stem cell transplant recipients at 2 hospitals, surveillance with polymerase chain reaction (PCR) (blood) was instituted. Rate of reactivation among seropositive recipients was 2.2 and 16%. Parasitemia was successfully managed with preemptive treatment. For seropositive recipients unable to take prophylaxis, toxoplasma PCR surveillance should be routinely performed.
Medical subject headings
- Pre-Exposure Prophylaxis
- Stem Cell Transplantation
- Toxoplasma
- Toxoplasmosis