Mitochondria: Masters of Epigenetics.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 27203109.
- Also identified by DOI 10.1016/j.cell.2016.05.021 and PMC identifier 5383427.
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Abstract
Accumulating evidence argues that aging exerts a profound influence on epigenetics, and vice versa. A pair of studies by Merkwirth et al. and Tian et al. now provide insights on how mitochondrial stress experienced by C. elegans larvae propagates a specific and persistent epigenetic response that protects adult cells and extends lifespan.
Medical subject headings
- Caenorhabditis elegans
- Caenorhabditis elegans Proteins