SnapShot: Microglia in Disease.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 27203115.
- Also identified by DOI 10.1016/j.cell.2016.05.036.
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Abstract
The development and maintenance of the central nervous system is dependent upon regulated, homeostatic actions of microglia, which sculpt and refine neuronal circuitry. By contrast, dysregulation of microglia contributes to the pathology of neurodevelopmental disorders such as autism spectrum disorders; neurodegenerative disorders such as Alzheimer's disease; and schizophrenia and chronic neuropathic pain.
Medical subject headings
- Microglia
- Nervous System
- Nervous System Diseases