Lysosomal Acid Lipase Activity Is Reduced Both in Cryptogenic Cirrhosis and in Cirrhosis of Known Etiology.
Where this comes from
- Record sourced from PubMed, PMID 27219619.
- Also identified by DOI 10.1371/journal.pone.0156113 and PMC identifier 4878774.
- Licence recorded as CC BY.
- The licence permits redistribution, so the abstract is shown in full and the full text is available from the publisher.
Abstract
Liver cirrhosis is characterized by a severe acquired reduction of LAL-activity, the precise causes and consequences of which need to be further addressed. DBS-determined lysosomal enzyme activities seem to be affected by white blood cell and platelet counts, and the specificity of these tests can be reduced when applied to determined populations, such as cirrhotics.
Medical subject headings
- Liver Cirrhosis
- Polymorphism, Single Nucleotide
- Sterol Esterase