A randomized comparative study of topical versus intravenous tranexamic acid administration in enhanced recovery after surgery (ERAS) total knee replacement.
rct · Level II
Where this comes from
- Record sourced from PubMed, PMID 27222617.
- Also identified by DOI 10.1016/j.jor.2016.03.007 and PMC identifier 4821446.
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Abstract
The aim of this study was to compare the topical to IV tranexamic acid (TXA) administration of the same dose, given at the same time in patients who underwent TKR using an enhanced recovery after surgery (ERAS) regime. Ninety patients were randomized in control group, and IV and topical application groups received 1 g TXA. Blood loss and transfusion requirements in control group were statistically higher compared to both TXA groups (p < 0.05). Length of stay was the same in all groups. TXA reduced significantly the blood loss and the need for transfusion in ERAS primary unilateral TKR.
Anatomy
- knee