Liposclerosing myxofibrous tumor: A series of 9 cases and review of the literature.
case_series · Level IV
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- Record sourced from PubMed, PMID 27222619.
- Also identified by DOI 10.1016/j.jor.2016.03.003 and PMC identifier 4821442.
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Abstract
Liposclerosing myxofibrous primary bone tumor is a rare benign bone lesion that was characterized by complex mixture of various histological elements. We have studied the radiological, clinical and pathological features of nine patients with this disorder. Pain and limping were the main symptoms. Radiographic images typically showed a geographic lytic lesion with thick sclerotic margin, reflecting a pattern of slow growth. Histological sections revealed a polymorphic neoplasia characterized by predominant proliferation of stellate and fusiform cells aimed the myxoid matrix. These features suggest that the lesion may represent a variant of fibrous dysplasia with a high risk of malignant transformation.