Epigenome-wide association study links site-specific DNA methylation changes with cow's milk allergy.

Hong, Xiumei; Ladd-Acosta, Christine; Hao, Ke; Sherwood, Ben; Ji, Hongkai; Keet, Corinne A; Kumar, Rajesh; Caruso, Deanna et al. · J Allergy Clin Immunol · 2016

other · Level V

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Abstract

We demonstrates that DNA methylation alterations at multiple genes, including those in the TH<sub>1</sub>-TH<sub>2</sub> pathways and some novel genes, are associated with cow's milk allergy (CMA), which shed new light on the epigenetic underpinnings of CMA.

Medical subject headings