Treating Liver Fibrosis: (Re)Programmed to Succeed.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 27257752.
- Also identified by DOI 10.1016/j.stem.2016.05.007.
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Abstract
Two papers (Rezvani et al., 2016; Song et al., 2016) in this issue of Cell Stem Cell use transcription-factor-mediated reprogramming to convert liver myofibroblasts into hepatocyte-like cells in mice. Moreover, murine models of fibrotic and cholestatic liver injury were used to demonstrate that this approach has potential for treatment of liver cirrhosis.
Medical subject headings
- Hepatocytes
- Liver Cirrhosis