Fat Decisions: Leptin Regulates Bone versus Fat in the Marrow.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 27257753.
- Also identified by DOI 10.1016/j.stem.2016.05.006.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Leptin is an adipocyte-derived hormone involved in energy sensing. In this issue of Cell Stem Cell, Yue et al. (2016) show that leptin is a physiologic signal that acts directly on Leptin-Receptor-expressing mesenchymal stromal cells in adult bone marrow to influence their lineage allocation in vivo, inhibiting bone formation and inducing marrow adipogenesis.
Medical subject headings
- Bone Marrow
- Leptin