Closing in on Mass Production of Mature Human Beta Cells.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 27257758.
- Also identified by DOI 10.1016/j.stem.2016.05.014.
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Abstract
Human pluripotent stem cell differentiation protocols based on mimicking developmental pathways are getting close to generating fully fledged pancreatic endocrine cells, including insulin-producing beta cells. However, challenges remain in identifying pathways to trigger the attainment of robust glucose responsiveness that occurs postnatally in beta cells.
Medical subject headings
- Cell Culture Techniques
- Insulin-Secreting Cells