Human Pluripotent Stem Cells: Myths and Future Realities for Liver Cell Therapy.

Goldman, Orit; Gouon-Evans, Valerie · Cell Stem Cell · 2016

basic_science · Level V

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Abstract

The severe shortage of organ donors for treating patients with liver disease has prompted in vitro efforts to produce the main functional cells of the liver: hepatocyte-like cells (Hep cells). We consider the key challenges posed by various stem cell technologies and liver pathologies for developing clinically useful Hep cells.

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