DBSI server: DNA binding site identifier.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 27259543.
- Also identified by DOI 10.1093/bioinformatics/btw315.
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Abstract
: Protein-nucleic acid interactions are among the most important intermolecular interactions in the regulation of cellular events. Identifying residues involved in these interactions from protein structure alone is an important challenge. Here we introduce the webserver interface to DNA Binding Site Identifier (DBSI), a powerful structure-based SVM model for the prediction and visualization of DNA binding sites on protein structures. DBSI has been shown to be a top-performing model to predict DNA binding sites on the surface of a protein or peptide and shows promise in predicting RNA binding sites. Server is available at http://dbsi.mitchell-lab.org jcmitchell@wisc.edu Supplementary data are available at Bioinformatics online.
Medical subject headings
- Protein Binding
- Protein Conformation