Persistent nodal histoplasmosis in nuclear factor kappa B essential modulator deficiency: Report of a case and review of infection in primary immunodeficiencies.

Lovell, Jana P; Foruraghi, Ladan; Freeman, Alexandra F; Uzel, Gulbu; Zerbe, Christa S; Su, Helen; Hsu, Amy P; Holland, Steven M · J Allergy Clin Immunol · 2016

case_report · Level V

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Abstract

In the absence of acquired or secondary immunosuppression, mutations causing failure to properly activate the IL-12/IFN-γ pathway, NF-κB, or STAT3 should be excluded in patients presenting with severe histoplasmosis.

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