A Novel Peptide Hydrogel for an Antimicrobial Bandage Contact Lens.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 27276231.
- Also identified by DOI 10.1002/adhm.201600258.
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Abstract
A peptide hydrogel with an antimicrobial activity is developed as a bandage contact lens. The antimicrobial activity is enhanced with the addition of the biomolecules penicillin G or poly-ε-lysine and is positive against Staphylococcus aureus and Escherichia coli. The lens is also noncytotoxic toward a human corneal epithelial cell line and as a consequence is of great potential as a drug-eluting bandage lens replacing conventional corneal ulcer treatment.
Medical subject headings
- Anti-Bacterial Agents
- Escherichia coli
- Hydrogels
- Penicillin G
- Polylysine
- Staphylococcus aureus