PGMA-Based Star-Like Polycations with Plentiful Hydroxyl Groups Act as Highly Efficient miRNA Delivery Nanovectors for Effective Applications in Heart Diseases.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 27297033.
- Also identified by DOI 10.1002/adma.201602319.
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Abstract
Poly(glycidyl methacrylate)-based star-like polycations with rich hydrophilic hydroxyl groups can efficiently transfer miRNA into primary cardiac fibroblasts for effective applications in cardiac diseases, such as inhibition of cardiac fibrosis and hypertrophy.
Medical subject headings
- Heart Diseases
- MicroRNAs
- Polyamines
- Polymethacrylic Acids