Mitochondria Apply the Brake to Viral Immunity.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 27304497.
- Also identified by DOI 10.1016/j.cmet.2016.05.018.
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Abstract
The development and function of cytotoxic CD8 T cells (CTLs), which provide immunity to viral infections, are regulated by changes in mitochondrial respiration. Champagne et al. (2016) describe a new mechanism through which mitochondrial metabolism controls production of ATP required for the secretion of critical anti-viral molecules by CTLs.
Medical subject headings
- Immunity
- Mitochondria
- Virus Diseases