Immunostimulatory Monoclonal Antibodies and Immunomodulation: Harvesting the Crop.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 27308833.
- Also identified by DOI 10.1158/0008-5472.CAN-15-3279.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
The recent approval by the FDA of the combination of anti-CTLA4 and anti-PD-1 mAbs for the treatment of BRAF-unmutated unresectable or metastatic melanoma is a landmark for the development of cancer immunotherapy. On October 18 to 22, 2015, a symposium was held in Pamplona (Spain) to present and discuss the basic and clinical discoveries that have brought us to this milestone and to explore other targets and immunotherapy strategies aimed at attaining more efficacious oncology practice in the short term. Cancer Res; 76(10); 2863-7. ©2016 AACR.
Medical subject headings
- Antibodies, Monoclonal
- CTLA-4 Antigen
- Immunomodulation
- Immunotherapy
- Melanoma
- Programmed Cell Death 1 Receptor