Ozone primes alveolar macrophage-derived innate immunity in healthy human subjects.

Frush, Benjamin W; Li, Zhuowei; Stiles, Jane V; Cotter, Sarah F; Shofer, Scott L; Foster, W Michael; Hollingsworth, John W; Tighe, Robert M · J Allergy Clin Immunol · 2016

other · Level V

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Abstract

The present study demonstrates that acute ozone exposure of healthy human subjects enhances lung immune responses to subsequent bacterial stimuli. This highlights common air pollutant exposures as modifiers of the intensity of pulmonary immune activation.

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