In Situ Patterning of Microfluidic Networks in 3D Cell-Laden Hydrogels.
basic_science · Level V
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- Record sourced from PubMed, PMID 27334545.
- Also identified by DOI 10.1002/adma.201601099.
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Abstract
Focalized short-pulsed lasers have sufficient power to generate micrometer-sized cavities in various hydrogels. An in situ technique based on laser ablation to fabricate intricate microfluidic networks in biocompatible gels without manual handling is presented. This method is fully compatible with 3D cell culture and opens up unprecedented opportunities for cell biology, developmental biology, and stem-cell-based tissue engineering.