Modification of PDMS to fabricate PLGA microparticles by a double emulsion method in a single microfluidic device.
basic_science · Level V
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- Record sourced from PubMed, PMID 27334791.
- Also identified by DOI 10.1039/c6lc00437g.
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Abstract
We present an easy, durable method to generate a partially hydrophilic/hydrophobic poly(dimethylsiloxane) (PDMS) microfluidic device. The functionality of this device was assessed in a double flow focusing design to fabricate core-shell structured poly(lactic-co-glycolic acid) (PLGA) microparticles (MPs).