Mitochondrial Networking in T Cell Memory.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 27368094.
- Also identified by DOI 10.1016/j.cell.2016.06.035.
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Abstract
T-lymphocytes show large changes in ATP demand and nutrient utilization, imposed by their different roles as T memory and T effector cells. Therefore, T cell remodeling represents a bioenergetic challenge to mitochondria. New work from Buck et al. links changes in mitochondrial shape to T cell fate choice.
Medical subject headings
- Mitochondria
- T-Lymphocytes