Negative results in phase III trials of complex interventions: cause for concern or just good science?
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 27369475.
- Also identified by DOI 10.1192/bjp.bp.115.179747.
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Abstract
Not all interventions that show promise in exploratory trials will be supported in phase III studies. But the high failure rate in recent trials of complex mental health interventions is a concern. Proper consideration of trial processes and greater use of adaptive trial designs could ensure better use of available resources.
Medical subject headings
- Clinical Trials, Phase III as Topic