Biomimetic Immuno-Magnetosomes for High-Performance Enrichment of Circulating Tumor Cells.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 27376951.
- Also identified by DOI 10.1002/adma.201601643.
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Abstract
A novel biomimetic immuno-magnetosome (IMS) is developed by coating a leukocyte membrane (decorated with anti-epithelial cell-adhesion molecule antibody) on a magnetic nanocluster. In addition to the good stability and magnetic controllability, the IMS also exhibits satisfactory binding avidity to circulating tumor cells but stealth property to leukocytes. As a result, rare tumor cells can be effectively enriched with undetectable leukocyte background.
Medical subject headings
- Biomimetic Materials
- Cell Separation
- Magnetosomes
- Neoplastic Cells, Circulating