Iron Supplementation for Chemotherapy-Induced Anemia in Patients Receiving Erythropoiesis-Stimulating Agents.
meta_analysis · Level I
Where this comes from
- Record sourced from PubMed, PMID 27387766.
- Also identified by DOI 10.1001/jamaoncol.2016.1864.
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Abstract
What are the benefits and harms of iron supplementation alone and as an adjunct to erythropoiesis-stimulating agents (ESAs) compared with ESA alone in the treatment of chemotherapy-induced anemia? Addition of iron to ESAs improves hematopoietic response, reduces the need for red blood cell transfusions, increases hemoglobin levels, and seems to be well tolerated. The subgroup analyses suggest the superiority of parenteral iron over oral iron supplementation in the treatment of chemotherapy-induced anemia.
Medical subject headings
- Anemia
- Antineoplastic Agents
- Erythropoiesis
- Erythropoietin
- Hematinics