Myocardial Ischemia: Lack of Coronary Blood Flow or Myocardial Oxygen Supply/Demand Imbalance?
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 27390331.
- Also identified by DOI 10.1161/CIRCRESAHA.116.308925.
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Abstract
Regional myocardial blood flow and contractile function in ischemic myocardium are well matched, and there is no evidence for an oxygen supply/demand imbalance. Thus, myocardial ischemia is lack of coronary blood flow with electric, functional, metabolic, and structural consequences for the myocardium. All therapeutic interventions must aim to improve blood flow to ischemic myocardium as much and as quickly as possible.
Medical subject headings
- Coronary Circulation
- Myocardial Ischemia
- Myocardium
- Oxygen Consumption