Determination of Personalized IOL-Constants for the Haigis Formula under Consideration of Measurement Precision.
Where this comes from
- Record sourced from PubMed, PMID 27391100.
- Also identified by DOI 10.1371/journal.pone.0158988 and PMC identifier 4938522.
- Licence recorded as CC BY.
- The licence permits redistribution, so the abstract is shown in full and the full text is available from the publisher.
Abstract
The capabilities of a weighted least squares approach for the optimization of the intraocular lens (IOL) constants for the Haigis formula are studied in comparison to an ordinary least squares approach. The weights are set to the inverse variances of the effective optical anterior chamber depth. The effect of random measurement noise is simulated 100000 times using data from N = 69 cataract patients and the measurement uncertainty of two different biometers. A second, independent data set (N = 33) is used to show the differences that can be expected between both methods. The weighted least squares formalism reduces the effect of measurement error on the final constants. In more than 64% it will result in a better approximation, if the measurement errors are estimated correctly. The IOL constants can be calculated with higher precision using the weighted least squares method.
Medical subject headings
- Lens, Crystalline
- Models, Theoretical
- Optometry