Pink Light on Mitochondria in Autoimmunity and Parkinson Disease.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 27411006.
- Also identified by DOI 10.1016/j.cmet.2016.06.022 and PMC identifier 4993039.
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Abstract
Mitochondrial dysfunction and T cell autoimmunity have been independently implicated in Parkinson disease pathogenesis. In a recent publication in Cell, Matheoud et al. (2016) link them by describing a new mechanism, activated in familial forms of Parkinson disease, in which mitochondrial proteins are processed for recognition by CD8+ T cells.
Medical subject headings
- Autoimmunity
- Parkinson Disease