Reactive Oxygen Species: Physical, Chemical, and Biological Structures based on ROS-Sensitive Moieties that are Able to Respond to Oxidative Microenvironments (Adv. Mater. 27/2016).
review · Level V
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- Also identified by DOI 10.1002/adma.201670187.
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Abstract
On page 5553, C. Tapeinos and A. Pandit review the properties of reactive oxygen species (ROS)-sensitive moieties which can respond to oxidative conditions inside cells. ROS-sensitive chemical structures, shown in the background of the image, are currently used in the biomedical field as drug-delivery systems, imaging probes, prochelators, and prodrugs for imaging and treatment of various diseases.