Metal-Organic Framework Coatings as Cytoprotective Exoskeletons for Living Cells.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 27414706.
- Also identified by DOI 10.1002/adma.201602335.
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Abstract
The biomimetic mineralization of metal-organic framework (MOF) material on living cells is reported. ZIF-8 can be crystallized on a living cell surface as an exoskeleton that offers physical protection while allowing transport of essential nutrients, thus maintaining cell viability. The MOF shell prevents cell division, leading to an artificially induced pseudo-hibernation state. Cellular functions can be fully restored upon MOF removal.
Medical subject headings
- Cytoprotection
- Metal-Organic Frameworks
- Protective Agents