Metabolic Precision Medicines: Curing POMC Deficiency.
case_report · Level V
Where this comes from
- Record sourced from PubMed, PMID 27452145.
- Also identified by DOI 10.1016/j.cmet.2016.07.006.
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Abstract
Pro-opiomelanocortin deficiency is a rare cause of severe intractable obesity. Two patients have experienced dramatic weight loss in response to setmelanotide, a melanocortin-4 receptor activator. The drug has potential in broader populations, but caution is warranted as it may act at other melanocortin receptors.
Medical subject headings
- Precision Medicine
- Pro-Opiomelanocortin