Broadening Horizons: New Antibodies Against Influenza.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 27471961.
- Also identified by DOI 10.1016/j.cell.2016.07.023.
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Abstract
Seasonal influenza vaccine formulation efforts struggle to keep up with viral antigenic variation. Two studies now report engineered or naturally occurring human antibodies targeting the influenza hemagglutinin (HA) stem, with exceptional neutralizing breadth (Joyce et al., 2016; Kallewaard et al., 2016). Antibodies with similar structural features are elicited in multiple subjects, suggesting that modified vaccine regimens could provide broad protection.
Medical subject headings
- Hemagglutinin Glycoproteins, Influenza Virus
- Influenza, Human