Deteriorating Infrastructure in the Aged Muscle Stem Cell Niche.

Rodgers, Joseph T · Cell Stem Cell · 2016

basic_science · Level V

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Abstract

Following an injury, the extracellular matrix (ECM) undergoes dramatic remodeling to facilitate tissue repair. In a new study, Lukjanenko and colleagues show how an age-associated change in this process affects the regenerative ability of muscle stem cells (MuSCs).

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